This year's South Carolina Sales Tax Free Weekend will run from Friday, August 5th through Sunday, August 7th.
During the annual Sales Tax Holiday, a variety of purchases are exempt from the state’s 6% sales tax and any applicable local taxes. Tax-free items range from clothing, accessories, and shoes to school supplies, backpacks, and computers. As long as an item is eligible, it is tax-free whether purchased in-store or online.
You can get more information here.
A list of exempt items can be found here.