In February, thousands of bold, pants-less participants will hit the streets in multiple cities across the U.S. for the annual Cupid’s Undie Run, a one-of-a-kind fundraiser for the Children’s Tumor Foundation (CTF). This unforgettable event raises awareness for NF and funds vital research to combat the rare genetic condition that causes tumors to grow all over the body. The Charleston event will take place on Saturday, Feb. 14, 2026, from noon until 4 p.m., at Loggerhead's Beach Grill on Folly Beach (123 W Ashley Ave).
Cupid’s Undie Run keeps it simple: raise money for research, run your heart out, and have a great time doing it. The day starts with music, laughter, and that “are we really doing this?” buzz before everyone takes off for a quick “mile-ish” dash – some in underwear, others in costumes, all in for the cause.
Then it’s back inside for a party featuring dancing, drinks, food, celebrating, and more.
NF is a group of genetic conditions that causes tumors to grow on nerves throughout the body and affects 1 in 2,000 births, which is about 4 million people worldwide. Anyone can be born with NF across all populations, and it affects everyone differently. NF can cause a wide range of systems, including blindness, deafness, bone abnormalities, disfigurement, learning challenges, disabling pain, or cancer.
The Children’s Tumor Foundation (CTF) is a global leader and catalyst for advancing treatments for neurofibromatosis and schwannomatosis (collectively known as NF). As the driving force behind NF drug discovery and development, CTF unites patients, researchers, clinicians, and industry to propel innovative therapies from the lab to the clinic. CTF is laser-focused on delivering approved treatments and ultimately finding